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Certified SPRAVATO® REMS Treatment Center
SPRAVATO® Treatment
in Evansville, IN
At Allure Wellness Center in Evansville, IN, we offer SPRAVATO® (esketamine) for adults living with treatment-resistant depression. This FDA-approved nasal spray is used alongside an oral antidepressant and is designed for patients who have not found relief with traditional medications. Administered under medical supervision, SPRAVATO® may provide rapid improvement in depressive symptoms and support long-term mental health stability.
Serving Evansville
10+
24Hr
Spravato® Onset Possible
FDA
Approved Treatment
Google Rating
4.8
NEW TREATMENT AVAILABLE!
SPRAVATO®
(Esketamine)
Treatment in Evansville
Innovative, FDA-approved relief for treatment-resistant depression — when antidepressants haven't been enough.
If you have struggled with depression and tried two or more antidepressants without adequate relief, you may have Treatment-Resistant Depression (TRD). Allure Wellness Center is proud to offer SPRAVATO® (esketamine) — the first and only FDA-approved nasal spray specifically designed for TRD. Unlike traditional antidepressants that target serotonin, SPRAVATO® works on the glutamate system via NMDA receptor antagonism, offering a completely different pathway to relief.
FDA-approved since 2019; expanded to monotherapy in January 2025
Rapid symptom relief — as early as 24 hours after first treatment
Proven superior to placebo at both 24 hours and 4 weeks
Over 100,000 patients treated in the U.S
Available with or without an oral antidepressant
Covered by many commercial insurance plans, Medicare & Medicaid
Step-by-Step
How SPRAVATO® Treatment Works
Each session takes place in our comfortable, supervised office environment. Here is what to expect:
1
2
3
4
5
Consultation
Check-In
Self-Administer
2-Hour Monitor
Go Home
Your PMHNP reviews your history and confirms SPRAVATO® is right for you.
Blood pressure and mental state are assessed before treatment begins.
You self-administer the nasal spray under your provider's supervision.
Our staff monitors your vitals and well-being for at least two hours.
A trusted driver takes you home. No driving on treatment day.
Treatment Schedule
SPRAVATO® Dosing Schedule
Phase 1 — Induction
First Month
2x / Week
8 sessions total to establish therapeutic effect and build response.
Phase 2 — Consolidation
Second Month
1x / Week
4 sessions to consolidate improvement and maintain response.
Phase 3 — Maintenance
Month 3 Onward
Every 1–2 Weeks
Ongoing maintenance tailored to your individual response and needs.
Am I a Candidate?
Who Is SPRAVATO®
Right For?
You may be a candidate for SPRAVATO® treatment at Allure Wellness Center if you:
Have been diagnosed with Major Depressive Disorder (MDD)
Are seeking a faster-acting treatment option
Have tried at least2 different oral antidepressants without adequate relief
Are experiencing MDD with acute suicidal ideation or behavior
Are an adult (18 years or older)
Are willing to attend in-office sessions with a designated driver
FDA-Approved SPRAVATO® Provider
REMS-Certified Treatment Center
Expert PMHNPs On Staff
Insurance Coverage Available
3 Convenient Evansville Locations
Important Safety Information
SPRAVATO® (esketamine) is a controlled substance available only through a restricted program called the SPRAVATO REMS. It is administered in a certified healthcare setting under direct medical supervision. Patients must be monitored for at least 2 hours after each session and must not drive or operate heavy machinery on the day of treatment.
SPRAVATO may cause serious side effects including: dissociation, dizziness, nausea, sedation, vertigo, and increased blood pressure. It has potential for abuse and misuse. It is not appropriate for all patients.
Our clinic is a certified SPRAVATO treatment center. A full psychiatric evaluation is required before treatment begins. Please speak with your provider about whether SPRAVATO is right for you.
Take the First Step Toward Recovery Today
Don't let mental health challenges hold you back. Reaching out is the first step toward healing and wellness. Our compassionate team of PMHNPs and mental health professionals is ready to support you on your journey to a happier, healthier life.
Whether you're experiencing anxiety, depression, addiction, or any other mental health concern, we're here to help. Call or book an appointment online today to get started with a psychiatric evaluation.